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The native contrast of optical coherence tomography (OCT) data in dense tissues can pose a challenge for clinical decision making. Uniform fluorescent silica-dye microspheres have been prepared by coating preformed monodispersed silica particles with silica layers containing rhodamine 6G or acridine orange. The threshold 10-minute-long activation results in the increased size and viagra prices in washington dc lighter staining of nerve cells. Hence the micromachined fluidic structure must allow for both optical access to the microbeads and fluid flow through the micromachined cavities that serve as the microreactors/analysis chambers.

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