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CRISPR-mediated deletion of members of the 4E-BP family in murine erythroid cells rendered them resistant to mTORC1 and LAT3 inhibition and restored hemoglobin production. An evaluation of quantitative agarose-gel electrophoresis of serum lipoproteins. Endothelin reduced basal skin blood flow and reversed the increased blood flow induced by a vasodilator.

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